Ibrahim N B, Briggs J C, Corbishley C M
Cancer. 1984 Oct 15;54(8):1645-61. doi: 10.1002/1097-0142(19841015)54:8<1645::aid-cncr2820540828>3.0.co;2-q.
Primary extrapulmonary tumors with histologic features indistinguishable from bronchogenic oat cell carcinoma are appearing with increasing frequency in the literature. These tumors have been described in the esophagus, stomach, pancreas, larynx, hypopharynx, salivary glands, nasal cavity and paranasal sinuses, thymus, small and large bowel, uterine cervix, endometrium, breast, prostate, urinary bladder, and skin. It is now widely believed that oat cell carcinoma is a poorly differentiated counterpart of carcinoid tumor and that both originate from an endocrine cell system. In this article, the authors review all cases of extrapulmonary oat cell carcinomas, which they were able to find in the English literature, and report personally studied examples of these tumors, occurring in the esophagus, stomach and urinary bladder. A closely related, if not identical, tumor arising in the skin is also described. It is emphasized that a wider recognition of these tumors is likely to lead to their more frequent diagnosis and possible treatment.
原发性肺外肿瘤，其组织学特征与支气管源性燕麦细胞癌难以区分，在文献中出现的频率越来越高。这些肿瘤已在食管、胃、胰腺、喉、下咽、唾液腺、鼻腔和鼻窦、胸腺、小肠和大肠、子宫颈、子宫内膜、乳腺、前列腺、膀胱及皮肤中被描述。现在人们普遍认为燕麦细胞癌是类癌肿瘤的低分化对应物，两者均起源于内分泌细胞系统。在本文中，作者回顾了他们在英文文献中所能找到的所有肺外燕麦细胞癌病例，并报告了亲自研究的发生于食管、胃和膀胱的这些肿瘤的实例。还描述了一种即使不完全相同但密切相关的皮肤肿瘤。强调对这些肿瘤更广泛的认识可能会导致其更频繁的诊断及可能的治疗。
