Lockman H A, Galen J E, Kaper J B
J Bacteriol. 1984 Sep;159(3):1086-9. doi: 10.1128/jb.159.3.1086-1089.1984.
The nucleotide sequence of the DNA encoding the ADP-ribosyltransferase (A1) fragment of cholera enterotoxin was determined. A putative precursor of the A1 peptide contains an 18-amino acid leader peptide, and the mature A1 peptide contains 194 amino acids. The primary structure of the A1 fragment from cholera enterotoxin is more related to that from a human enterotoxigenic Escherichia coli than to that from a porcine enterotoxigenic E. coli.
测定了编码霍乱肠毒素ADP-核糖基转移酶(A1)片段的DNA的核苷酸序列。A1肽的假定前体包含一个18个氨基酸的前导肽,成熟的A1肽包含194个氨基酸。霍乱肠毒素A1片段的一级结构与人类产肠毒素大肠杆菌的A1片段一级结构的相关性,高于与猪产肠毒素大肠杆菌的A1片段一级结构的相关性。