Local energized proton hypotheses of mitochondrial oxidative phosphorylation.

Two hypotheses are compared each interpreting mitochondrial energy transduction in terms of a localized form of proton activity. Their differences are seen to be profound and far-reaching. It is concluded that the "chemiosmotic/local energized proton dialogue" as conducted hitherto has offered a very incomplete and restricted analysis of the problems of mitochondrial oxidative phosphorylation.