Timashev S F
Biofizika. 1981 Nov-Dec;26(6):1027-32.
Charged particles (electrons and protons) transport in the respiratory chain of mitochondria in the process of oxidative phosphorylation is considered. It is shown that no kinetic difficulties appear in such transport (including proton transport against the mean field of the membrane) because the free energy of redox processes with participation of cytochrome may be used for charge separation and formation of protons in the region of internal fields. These fields arise from separation of charges in heme and depend on the orientation of the heme plane in respect to the membrane surface, and they cause the initial stages of proton transport in the direction necessary for oxidative phosphorylation. It is also shown that conformation changes of the albumin chains which accompany reduction and oxidation of cytochromes determine the transport of charges along the respiratory chain.
考虑了氧化磷酸化过程中带电粒子（电子和质子）在线粒体呼吸链中的传输。结果表明，这种传输（包括质子逆膜平均场的传输）不存在动力学困难，因为细胞色素参与的氧化还原过程的自由能可用于电荷分离和在内场区域形成质子。这些场由血红素中的电荷分离产生，并取决于血红素平面相对于膜表面的取向，它们导致质子沿氧化磷酸化所需方向传输的初始阶段。还表明，伴随细胞色素还原和氧化的白蛋白链构象变化决定了沿呼吸链电荷的传输。
