布氏锥虫可变表面抗原基因的明显不连续转录
Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes.
作者信息
Campbell D A, Thornton D A, Boothroyd J C
出版信息
Nature. 1984;311(5984):350-5. doi: 10.1038/311350a0.
Abstract
The repeated mini-exon sequence that encodes the first 35 base pairs of all variant surface antigen mRNAs of Trypanosoma brucei directs the synthesis of a discrete 137-nucleotide transcript. It thus seems that variant surface antigen mRNAs are transcribed discontinuously, and we present two alternative models for how this might occur.
摘要
编码布氏锥虫所有可变表面抗原mRNA前35个碱基对的重复小外显子序列指导合成一种离散的137个核苷酸的转录本。因此，可变表面抗原mRNA似乎是间断转录的，我们提出了两种关于其可能发生方式的替代模型。
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