Nagy J I, Buss M, LaBella L A, Daddona P E
Neurosci Lett. 1984 Jul 27;48(2):133-8. doi: 10.1016/0304-3940(84)90008-9.
Adenosine deaminase (ADA) was detected immunohistochemically in neuronal cell bodies of dorsal root ganglia (DRG) of the rat. ADA-immunoreactivity was confined exclusively to small type B ganglion neurons in cervical, thoracic and lumbar sensory ganglia; large type A neurons in sensory ganglia were devoid of immunostaining for ADA. It was consistently found that only a small proportion of type B neurons in DRG contain immunohistochemically detectable ADA. It is suggested that the expression of high ADA levels is a distinguishing feature of a subpopulation of type B DRG neurons and, further, that ADA in these neurons may reflect their utilization of purines (adenosine or adenine nucleotides) as transmitters or cotransmitters.
采用免疫组织化学方法在大鼠背根神经节（DRG）的神经元胞体中检测到了腺苷脱氨酶（ADA）。ADA免疫反应性仅局限于颈、胸和腰段感觉神经节中的小型B类神经节神经元；感觉神经节中的大型A类神经元没有ADA免疫染色。一直以来发现，DRG中只有一小部分B类神经元含有免疫组织化学可检测到的ADA。这表明高ADA水平的表达是B类DRG神经元亚群的一个显著特征，此外，这些神经元中的ADA可能反映了它们对嘌呤（腺苷或腺嘌呤核苷酸）作为递质或共递质的利用情况。
