Gögelein H, Koepsell H
Pflugers Arch. 1984 Aug;401(4):433-4. doi: 10.1007/BF00584351.
Planar bilayer membranes were made from commercially available lipids. With various lipids, originating from biological sources, such as egg yolk phosphatidylcholine, soybean phosphatidylcholine or bovine brain phosphatidylserine, spontaneously fluctuating channels could be observed. Spontaneous channel activity could not be observed in planar bilayers made from synthetic lipids, such as 1,2 diphytanoyl 3-sn-phosphatidylcholine. It is concluded that the observed channels are due to proteolipids, being present as impurities in the lipid material.
平面双层膜由市售脂质制成。使用源自生物来源的各种脂质，如蛋黄磷脂酰胆碱、大豆磷脂酰胆碱或牛脑磷脂酰丝氨酸，可观察到自发波动的通道。在由合成脂质如1,2-二植烷酰基-3-sn-磷脂酰胆碱制成的平面双层膜中未观察到自发通道活性。得出的结论是，观察到的通道是由于脂蛋白作为脂质材料中的杂质存在所致。
