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[单糖对精子膜净离子通量的影响。对获能的作用]

[Effect of monosaccharides on net ion fluxes across the sperm membrane. Contribution to capacitation].

作者信息

Glander H J, Dettmer D, Haake K W

出版信息

Zentralbl Gynakol. 1984;106(10):637-43.

PMID:6091365
Abstract

Monosaccharide supply, monosaccharide fluxes and ion fluxes play an important role in the process of capacitation of spermatozoa. Therefore we investigated the influence of D-glucose and D-fructose on the net -fluxes of Na+ and Rb+. The Na+ fluxes were very low and showed no alterations, when glucose or fructose were present in the incubation medium. On the other hand the net-Rb+-fluxes, which can be regarded as representative for the net-K+-fluxes, were energy dependent and ouabain-sensitive. Moreover D-glucose and D-fructose increased significantly the affinity of Rb+ towards its transport system. The specifity of these interactions is discussed.

摘要

单糖供应、单糖通量和离子通量在精子获能过程中发挥着重要作用。因此,我们研究了D-葡萄糖和D-果糖对Na⁺和Rb⁺净通量的影响。当孵育培养基中存在葡萄糖或果糖时,Na⁺通量非常低且无变化。另一方面,可被视为代表净K⁺通量的净Rb⁺通量是能量依赖性的且对哇巴因敏感。此外,D-葡萄糖和D-果糖显著增加了Rb⁺对其转运系统的亲和力。讨论了这些相互作用的特异性。

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