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单糖跨人类精子细胞膜的转运。II. D-果糖和D-葡萄糖摄取的基本特性。

Monosaccharide transport across membranes of human spermatozoa. II. Basic properties of D-fructose and D-glucose uptake.

作者信息

Glander H J, Dettmer D

出版信息

Andrologia. 1978 Jul-Aug;10(4):273-7.

PMID:717807
Abstract

D-glucose uptake by human spermatozoa shows like D-fructose uptake a hyperbolic kinetic. The affinities to the transport system are similar, but the maximal capacity of D-glucose transport is greater than the D-fructose transport. Both transport processes are inhibited by monoiodoacetate. Therefore these transports can be regarded as carrier-mediated active transports. The D-glucose transport moreover is inhibitable by ouabain and is influenced by extracellular Na+. These differences could be the expression that for both monosaccharides different transport systems exist. But the dependence of D-glucose and D-fructose uptake on the extracellular D-fructose-D-glucose-relation permits the conclusion that both systems interact with another.

摘要

人类精子对D-葡萄糖的摄取呈现出与D-果糖摄取相似的双曲线动力学。对转运系统的亲和力相似,但D-葡萄糖转运的最大能力大于D-果糖转运。两种转运过程均被单碘乙酸抑制。因此,这些转运可被视为载体介导的主动转运。此外,D-葡萄糖转运可被哇巴因抑制,并受细胞外钠离子影响。这些差异可能表明存在针对两种单糖的不同转运系统。但D-葡萄糖和D-果糖摄取对细胞外D-果糖-D-葡萄糖关系的依赖性表明,这两种系统相互作用。

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