[腺病毒的实验室检测方法。十一、运用酶联免疫吸附测定法检测结膜分泌物中的六邻体及抗六邻体IgA]
[Laboratory methods for adenoviruses. XI. Determination of hexon and antihexon-IgA in conjunctival secretions using ELISA].
作者信息
Kühn J, Wigand R, Hammer H J, Bruch P, Adrian T
出版信息
Zentralbl Bakteriol Mikrobiol Hyg A. 1984 Aug;257(3):426-32.
The possibility of a rapid diagnosis of adenovirus conjunctivitis was studied by demonstrating genus-specific adenovirus hexon antigen or antihexon IgA antibodies in conjunctival secretions by an ELISA. Hexon was found in 44% of about 100 patients with adenovirus conjunctivitis, proven by virus isolation, antihexon in 53%, either one or both in 69% of the conjunctival swabs from the acute phase. Hexon was found in the acute phase more frequently, antihexon in the convalescent phase. In patients with conjunctivitis of different etiology no hexon was found, whereas antihexon IgA was found in a few cases.
通过酶联免疫吸附测定法（ELISA）检测结膜分泌物中的属特异性腺病毒六邻体抗原或抗六邻体IgA抗体，研究了快速诊断腺病毒结膜炎的可能性。在约100例经病毒分离证实为腺病毒结膜炎的患者中，44%的患者结膜拭子在急性期检测到六邻体，53%检测到抗六邻体，69%检测到其中之一或两者皆有。六邻体在急性期更常见，抗六邻体在恢复期更常见。在不同病因的结膜炎患者中未检测到六邻体，但在少数病例中检测到抗六邻体IgA。
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