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胆管细胞癌伴多发肝囊肿

Cholangiocellular carcinoma associated with multiple liver cysts.

作者信息

Imamura M, Miyashita T, Tani T, Naito A, Tobe T, Takahashi K

出版信息

Am J Gastroenterol. 1984 Oct;79(10):790-5.

PMID:6091444
Abstract

A 46-year-old woman visited our outpatient clinic complaining of dull right hypochondrial pain. Ultrasonography revealed four cysts in the right lobe of the liver. Arteriography and CT could not determine whether these cysts were benign or malignant. Because one of these cysts contained chocolate-colored fluid, amebic abscess was suspected, and the cyst was drained. No amebae were found in the cultured exudate, and fresh bleeding continued; therefore, laparotomy was performed. A tumor was present on the surface of the liver. Right lobectomy was performed. The resected specimen contained one nonepithelialized cyst which was invaded by surrounding cholangiocellular carcinoma and three epithelialized cysts. Preoperative diagnosis of this kind of cholangiocellular carcinoma seems to be very difficult. Recently cholangiocellular carcinoma associated with developmental cysts has been classified as a new entity different from cystadenocarcinoma. Cholangiocarcinoma, which belongs to this group, seems to deserve special attention.

摘要

一名46岁女性因右季肋部隐痛前来我院门诊就诊。超声检查发现肝脏右叶有4个囊肿。动脉造影和CT检查无法确定这些囊肿是良性还是恶性。由于其中一个囊肿含有巧克力色液体,怀疑为阿米巴脓肿,遂对该囊肿进行了引流。培养的渗出物中未发现阿米巴原虫,且持续有新鲜出血;因此,进行了剖腹手术。肝脏表面有一个肿瘤。实施了右叶切除术。切除标本中包含一个未上皮化的囊肿,其被周围的胆管细胞癌侵犯,以及三个上皮化的囊肿。术前诊断这种胆管细胞癌似乎非常困难。最近,与发育性囊肿相关的胆管细胞癌已被归类为一种不同于囊腺癌的新实体。属于该组的胆管癌似乎值得特别关注。

相似文献

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Cholangiocellular carcinoma associated with multiple liver cysts.胆管细胞癌伴多发肝囊肿
Am J Gastroenterol. 1984 Oct;79(10):790-5.
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Cholangiocarcinoma coexisting with developmental liver cysts: a distinct entity different from liver cystadenocarcinoma.胆管癌与发育性肝囊肿并存:一种不同于肝囊腺癌的独特实体。
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引用本文的文献

1
A case of intrahepatic cholangiocarcinoma arising from a simple hepatic cyst via dysplasia and carcinomatous transformation.一例由单纯性肝囊肿经发育异常和癌变转变而来的肝内胆管癌病例。
Abdom Radiol (NY). 2022 Jun;47(6):1954-1960. doi: 10.1007/s00261-022-03493-6. Epub 2022 Mar 28.
2
Intrahepatic cholangiocarcinoma arising in autosomal dominant polycystic kidney disease.常染色体显性遗传性多囊肾病相关的肝内胆管癌
Virchows Arch. 2002 Jul;441(1):98-100. doi: 10.1007/s00428-002-0635-8. Epub 2002 Mar 26.
3
Adult polycystic liver disease: is fenestration the most adequate operation for long-term management?
成人多囊肝病:开窗术是长期治疗最恰当的手术方式吗?
Ann Surg. 1997 Mar;225(3):286-94. doi: 10.1097/00000658-199703000-00008.
4
Biliary carcinosarcoma arising in nonparasitic simple cyst of the liver.
Virchows Arch. 1994;424(3):331-5. doi: 10.1007/BF00194620.
5
Treatment of highly symptomatic polycystic liver disease. Preliminary experience with a combined hepatic resection-fenestration procedure.高度症状性多囊肝疾病的治疗。肝切除联合开窗术的初步经验。
Ann Surg. 1990 Jul;212(1):30-7. doi: 10.1097/00000658-199007000-00005.
6
Squamous carcinoma in the liver.肝脏鳞状细胞癌。
Gut. 1990 Nov;31(11):1333-4. doi: 10.1136/gut.31.11.1333.
7
A report of 5 cases of cystic bile duct carcinoma of the liver and proposal of a new classification.
Gastroenterol Jpn. 1991 Feb;26(1):80-9. doi: 10.1007/BF02779514.