Azizah N, Paradinas F J
Histopathology. 1980 Jul;4(4):391-400. doi: 10.1111/j.1365-2559.1980.tb02934.x.
We report one liver cystadenocarcinoma and two cholangiocarcinomas coexisting with developmental liver cysts. The cystadenocarcinoma was a solitary multilocular cyst with histological features similar to those seen in ovarian mucinous cystadenocarcinoma. In contrast, the other two tumours were a mixture of solid adenocarcinoma and multiple non-neoplastic cysts containing serous fluid and lined mainly by atrophic epithelium. In both these cases renal cysts were also present and in one case there was focal malignant change of the epithelium lining the cysts from which the solid adenocarcinoma could have originated. Our observations support the view that cholangiocarcinoma associated with developmental liver cysts is an entity different from liver cystadenocarcinoma.
我们报告了1例肝囊腺癌和2例与先天性肝囊肿并存的胆管癌。该囊腺癌为孤立性多房囊肿，组织学特征与卵巢黏液性囊腺癌相似。相比之下，另外2例肿瘤是实性腺癌与多个含有浆液、主要内衬萎缩上皮的非肿瘤性囊肿的混合体。在这2例中均存在肾囊肿，其中1例囊肿内衬上皮有局灶性恶性改变，实性腺癌可能起源于此。我们的观察结果支持以下观点，即与先天性肝囊肿相关的胆管癌是一种不同于肝囊腺癌的实体。
