原核生物移动遗传元件IS30的核苷酸序列。
Nucleotide sequence of the prokaryotic mobile genetic element IS30.
作者信息
Dalrymple B, Caspers P, Arber W
出版信息
EMBO J. 1984 Sep;3(9):2145-9. doi: 10.1002/j.1460-2075.1984.tb02104.x.
Abstract
The complete nucleotide sequence of the mobile genetic element IS30, a resident of Escherichia coli K12, is 1221 bp long. A large open reading frame, preceded by possible transcription and translation control signals, could encode a basic protein of 383 amino acids which might presumably function as transposase. No large in-frame open reading frame is present on the opposite strand. The 26 bp long terminal inverted repeats have some sequence homology with the c-end of the phage Mu genome and with the terminal inverted repeats of the Halobacterium halobium insertion element ISH50. The IS30 sequence has no significant homology with any other sequenced prokaryotic insertion sequences.
摘要
移动遗传元件IS30是大肠杆菌K12的一个常驻元件，其完整核苷酸序列长度为1221 bp。一个大的开放阅读框，前面有可能的转录和翻译控制信号，可编码一个由383个氨基酸组成的碱性蛋白，该蛋白可能作为转座酶发挥作用。相反链上不存在大的框内开放阅读框。26 bp长的末端反向重复序列与噬菌体Mu基因组的c末端以及嗜盐菌插入元件ISH50的末端反向重复序列有一些序列同源性。IS30序列与任何其他已测序的原核插入序列均无显著同源性。
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