Tarver R D, Richmond B D, Klatte E C
Radiology. 1984 Dec;153(3):689-92. doi: 10.1148/radiology.153.3.6093189.
To determine the role of brain CT in neurologically asymptomatic lung cancer patients, a review was made of the CT and clinical findings in 279 patients. Neurological status in these patients was categorized as (a) normal, (b) abnormal with specific signs and symptoms, and (c) abnormal with vague signs and symptoms. Brain metastases were found in 94.5% of patients (69/73) with specific abnormal neurological findings, 26.6% of patients (16/60) with vague neurological signs and symptoms, 11% of patients (10/92) with oat cell carcinoma and a normal neurological examination, and 40% of patients (8/20) with adenocarcinoma and a normal neurological examination. Brain metastasis was not seen on CT in the 29 patients with squamous cell carcinoma and a normal neurological examination. It is concluded that brain CT is useful for the detection of occult brain metastases, particularly oat cell carcinoma and adenocarcinoma, in neurologically asymptomatic lung cancer patients.
为确定脑部CT在神经系统无症状肺癌患者中的作用，对279例患者的CT及临床检查结果进行了回顾性分析。这些患者的神经状态分为：(a)正常；(b)有特定体征和症状的异常；(c)有模糊体征和症状的异常。在有特定神经异常表现的患者中，94.5%（69/73）发现脑转移；有模糊神经体征和症状的患者中，26.6%（16/60）发现脑转移；燕麦细胞癌且神经检查正常的患者中，11%（10/92）发现脑转移；腺癌且神经检查正常的患者中，40%（8/20）发现脑转移。在29例鳞状细胞癌且神经检查正常的患者中，CT未发现脑转移。结论是，脑部CT有助于检测神经系统无症状肺癌患者中隐匿性脑转移，尤其是燕麦细胞癌和腺癌。
