August J R
Vet Clin North Am Small Anim Pract. 1984 Sep;14(5):971-84. doi: 10.1016/s0195-5616(84)50102-8.
Mainly through studies inducing experimental infection of susceptible cats, significant advances have recently been made in our understanding of the pathogenesis of FIP. Much of this knowledge should not presently be directly extrapolated to field cases of FIP, because the route of infection and challenge dose and strain of virus may be significantly different. Advances in the prevention and treatment of FIP will depend greatly on clarification of the exact nature of the several coronaviruses affecting cats and the role of cell-mediated immunity in resistance to FIPV.
主要通过诱导易感猫发生实验性感染的研究,我们对猫传染性腹膜炎(FIP)发病机制的理解最近取得了重大进展。目前,这些知识中的大部分不应直接外推至FIP的实际病例,因为感染途径、攻击剂量以及病毒株可能存在显著差异。FIP预防和治疗方面的进展将在很大程度上取决于对影响猫的几种冠状病毒的确切性质以及细胞介导免疫在抵抗猫传染性腹膜炎病毒(FIPV)中的作用的明确。