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新型冠状病毒肺炎与眼科:最新进展

COVID-19 Disease and Ophthalmology: An Update.

作者信息

Amesty María A, Alió Del Barrio Jorge L, Alió Jorge L

机构信息

Oculoplastic Department, Vissum (Grupo Miranza), Alicante, Spain.

Cornea, Cataract and Refractive Surgery Unit, Vissum (Grupo Miranza), Alicante, Spain.

出版信息

Ophthalmol Ther. 2020 Sep;9(3):1-12. doi: 10.1007/s40123-020-00260-y. Epub 2020 May 22.

Abstract

The worldwide outbreak of the severe and acute respiratory coronavirus disease (COVID-19) caused by the coronavirus strain SARS-CoV-2 is currently the focal point of discussion due to the suffering this syndrome is causing to humanity. However, the ophthalmological implications of this syndrome has not yet been well described. Both eyes and tears as portals of entry and sources of contagion have been the subject of debate by many authors. The purpose of this review is to summarize the evidence currently available on COVID-19 and its ocular implications and manifestations, in both animals and humans, with the aim to facilitate prevention and educate the ophthalmological community on this subject. A review of the literature revealed that the results of some studies suggest that ocular symptoms commonly appear in patients with severe COVID-19 pneumonia and that it is possible to isolate the virus from the conjunctival sac of these patients. Conjunctivitis is not a common manifestation of the disease, but contact with infected eyes could be one route of transmission. Consequently, ophthalmologists need to have correct prevention strategies in place. Some guidelines regarding the prevention and management of ophthalmology clinics are reviewed. However, well-designed trials should be conducted to rule out other ocular manifestations that may result from COVID-19 infection and to understand the transmission of the virus through the eyes.

摘要

由严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引起的全球严重急性呼吸冠状病毒疾病(COVID-19)疫情,因其给人类带来的痛苦,目前成为了讨论的焦点。然而,该综合征的眼科影响尚未得到充分描述。眼睛和眼泪作为病毒进入途径及传染源一直是许多作者争论的主题。本综述的目的是总结目前关于COVID-19及其在动物和人类中的眼部影响和表现的现有证据,以便于预防并就该主题对眼科界进行教育。文献综述显示,一些研究结果表明,眼部症状常见于重症COVID-19肺炎患者,并且有可能从这些患者的结膜囊中分离出病毒。结膜炎并非该疾病的常见表现,但接触受感染的眼睛可能是一种传播途径。因此,眼科医生需要制定正确的预防策略。本文回顾了一些关于眼科诊所预防和管理的指南。然而,应开展精心设计的试验,以排除COVID-19感染可能导致的其他眼部表现,并了解病毒通过眼睛的传播情况。

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