McCracken R M, McFerran J B, McParland P J, McKillop E R
Vet Rec. 1984 Oct 6;115(14):348-52. doi: 10.1136/vr.115.14.348.
Twelve herds were investigated where outbreaks of clinical Aujeszky's disease had occurred. Clinical Aujeszky's disease was eliminated from all farms following vaccination. After vaccination was stopped in two of the six fattening herds virus was also apparently eradicated, judging from serological examination. These two herds were the smallest of the six fattening farms and size and the throughput of pigs may have contributed to apparent eradication of virus. In two of six breeding farms where controlled vaccination is still practised unvaccinated gilts and boars were seronegative. In this case possible eradication of infection may have resulted from either no excretion or insufficient production of virus from vaccinates to infect susceptible non-vaccinates. It is postulated that a properly controlled and monitored vaccination and culling programme may result in the eradication of disease and perhaps also infection from breeding herds experiencing Aujeszky's disease.
对12个曾发生过临床型奥耶斯基氏病疫情的猪群进行了调查。通过疫苗接种,所有猪场的临床型奥耶斯基氏病均被消除。在6个育肥猪群中的2个停止疫苗接种后,从血清学检查判断,病毒显然也被根除。这两个猪群是6个育肥猪场中规模最小的,猪场规模和生猪出栏量可能有助于病毒的明显根除。在仍实施控制疫苗接种的6个繁殖猪场中的2个,未接种疫苗的后备母猪和公猪血清学呈阴性。在这种情况下,感染可能得以根除,原因可能是接种疫苗的猪不排毒,或者产生的病毒不足以感染易感的未接种疫苗的猪。据推测,一个适当控制和监测的疫苗接种及淘汰计划可能会导致疾病的根除,甚至可能使感染从发生奥耶斯基氏病的繁殖猪群中消除。