Courty J, Courtois Y, Barritault D
Biochimie. 1984 Jun;66(6):419-28. doi: 10.1016/0300-9084(84)90076-2.
This article summarizes some of the data that have been accumulated on several growth factors. Biochemical and biological properties of the Epidermal, Fibroblast, Astrocytes and Tumor growth factors (EGF, FGF, AGF, TGF) and those of growth factors derived from Platelets (PDGF), Brain (BDGF, ECGF), Eye (EDGF) and Cartilage (CDGF) are reviewed, as well as the in vitro mechanism of action of EGF and PDGF. The in vivo effects of these growth factors, particularly the experiments achieved to understand the physiological or physiopathological significance are described. The potential interest of these molecules in pharmacology and their use as wound healing agents is discussed.
本文总结了一些关于几种生长因子积累的数据。综述了表皮生长因子、成纤维细胞生长因子、星形胶质细胞生长因子和肿瘤生长因子（EGF、FGF、AGF、TGF）以及来自血小板（PDGF）、脑（BDGF、ECGF）、眼（EDGF）和软骨（CDGF）的生长因子的生化和生物学特性，以及EGF和PDGF的体外作用机制。描述了这些生长因子的体内作用，特别是为了解其生理或病理生理意义而进行的实验。讨论了这些分子在药理学方面的潜在价值及其作为伤口愈合剂的用途。
