Goldman W F, Eyzaguirre C
Brain Res. 1984 Nov 12;321(2):337-40. doi: 10.1016/0006-8993(84)90189-6.
Rabbit carotid bodies were excised and the membrane potentials (MPs) of the glomus cells were recorded in vitro. Upstream injections of dopamine (DA; 25-250 micrograms) elicited a slow, long lasting depolarization in 76% of the cells studied. The remaining 24% were hyperpolarized by DA. Regardless of polarity, the DA-induced potential was associated with a significant increase in input resistance (Ro). On the other hand, changes in MP which were produced artificially by passing direct current through the recording electrode had little effect on Ro. It is concluded that DA alters the MP and Ro of glomus cells and that this may serve to modulate synaptic excitability within the carotid body.
切除兔的颈动脉体，并在体外记录球细胞的膜电位（MPs）。向颈动脉体上游注射多巴胺（DA；25 - 250微克），在所研究的细胞中，76%出现缓慢、持久的去极化。其余24%的细胞被DA超极化。无论极性如何，DA诱导的电位都伴随着输入电阻（Ro）的显著增加。另一方面，通过记录电极通直流电人为产生的MP变化对Ro影响很小。结论是，DA改变球细胞的MP和Ro，这可能有助于调节颈动脉体内的突触兴奋性。
