Sackmann E, Kotulla R, Heiszler F J
Can J Biochem Cell Biol. 1984 Aug;62(8):778-88. doi: 10.1139/o84-099.
The present paper deals with the curvature (or splay) elasticity of lipid bilayers and its possible consequences for the microscopic organization of membranes. Experimental studies of the microstructure of lipid-lipid and lipid-protein mixtures are reported and discussed in terms of this type of membrane elasticity. In particular, evidence is provided that the elastic distortion of lipid bilayers caused by the incorporation of proteins can lead to mechanisms of the indirect protein-protein interaction. Finally the question is discussed whether these mechanisms could also play a role for the formation of enzyme complexes in biological membranes.
本文探讨了脂质双层的曲率（或展布）弹性及其对膜微观结构可能产生的影响。报告并讨论了关于脂质-脂质和脂质-蛋白质混合物微观结构的实验研究，这些研究是基于这种类型的膜弹性进行的。特别地，有证据表明，蛋白质掺入引起的脂质双层弹性畸变可导致间接蛋白质-蛋白质相互作用机制。最后讨论了这些机制是否也可能在生物膜中酶复合物的形成过程中发挥作用。
