Kulinsky V I, Trufanova L V, Medvedev A E
FEBS Lett. 1984 Nov 5;177(1):143-5. doi: 10.1016/0014-5793(84)80999-0.
Treatment of rats or liver homogenates with catecholamines (isoproterenol or noradrenaline) increased activities of both NAD+ -dependent isocitrate dehydrogenase and NAD(P)+-transhydrogenase (in the direction of hydrogen transfer NADPH----NAD+) with no change in NADP+ -dependent isocitrate dehydrogenase. These effects were realized via beta-adrenoceptors. Cyclic AMP mimicked the catecholamine action on incubation with liver homogenate. The effects of catecholamines and cyclic AMP were not additive.
用儿茶酚胺（异丙肾上腺素或去甲肾上腺素）处理大鼠或肝匀浆，可增加NAD⁺依赖性异柠檬酸脱氢酶和NAD(P)⁺转氢酶（氢转移方向为NADPH→NAD⁺）的活性，而NADP⁺依赖性异柠檬酸脱氢酶的活性无变化。这些作用是通过β-肾上腺素能受体实现的。环磷酸腺苷（cAMP）在与肝匀浆孵育时模拟了儿茶酚胺的作用。儿茶酚胺和环磷酸腺苷的作用不是相加的。
