腹膜炎的短期抗生素治疗：比较头孢噻肟-甲硝唑与克林霉素-妥布霉素的前瞻性随机试验
Short-term antibiotherapy for peritonitis: prospective, randomized trial comparing cefotaxime-metronidazole and clindamycin-tobramycin.
作者信息
Biron S, Brochu G, Béland L, Bourque R A, Marceau P, Piché P, Potvin M
出版信息
J Antimicrob Chemother. 1984 Sep;14 Suppl B:213-6. doi: 10.1093/jac/14.suppl_b.213.
PMID:6094442
Abstract
The combination of cefotaxime and metronidazole has been suggested for the treatment of peritonitis. We compared their effectiveness with that of tobramycin and clindamycin. Since antibiotics have most of their beneficial effect within a few days a four day course was used and a randomized trial was undertaken. The effectiveness of the 4-day course was 86% and no difference was seen between the two groups of the study.
摘要
有人建议联合使用头孢噻肟和甲硝唑治疗腹膜炎。我们将它们的疗效与妥布霉素和克林霉素的疗效进行了比较。由于抗生素在几天内就能发挥大部分有益作用，因此采用了为期四天的疗程并进行了一项随机试验。该四天疗程的有效率为86%，且研究的两组之间未观察到差异。
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