大鼠肝脏醛缩酶B信使核糖核酸的核苷酸序列。
Nucleotide sequence of rat liver aldolase B messenger RNA.
作者信息
Tsutsumi K, Mukai T, Tsutsumi R, Mori M, Daimon M, Tanaka T, Yatsuki H, Hori K, Ishikawa K
出版信息
J Biol Chem. 1984 Dec 10;259(23):14572-5.
The nucleotide sequence of messenger RNA encoding rat liver aldolase B has been determined by sequence analysis using recombinant cDNAs cloned in bacterial plasmids. The sequence contains part of the 5'-untranslatable region (68 nucleotides), the entire coding region (1092 nucleotides), and the complete 3'-untranslatable region (387 nucleotides), excluding the poly(A) tail. A potential ribosomal-binding site is located about 30 nucleotides upstream from the initiation codon. The amino acid sequence of rat liver aldolase B is composed of 364 amino acids and has 70% homology with rabbit muscle aldolase A.
通过对克隆于细菌质粒中的重组cDNA进行序列分析，已确定了编码大鼠肝脏醛缩酶B的信使核糖核酸（mRNA）的核苷酸序列。该序列包含部分5'-非翻译区（68个核苷酸）、整个编码区（1092个核苷酸）以及完整的3'-非翻译区（387个核苷酸），不包括聚腺苷酸尾。一个潜在的核糖体结合位点位于起始密码子上游约30个核苷酸处。大鼠肝脏醛缩酶B的氨基酸序列由364个氨基酸组成，与兔肌肉醛缩酶A具有70%的同源性。
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