Winters W D, Guest G F, McAnear J T
J Dent Res. 1984 Nov;63(11):1306-9. doi: 10.1177/00220345840630111101.
Levels of immunoglobulin class-specific antibodies as determined by solid phase radioimmunoassays to herpes simplex virus type 1 (HSV-1), human adenovirus types 5, 21, and 31 and to Candida albicans in sera from untreated healthy dental patients were not significantly different from levels of these antibodies in sera from untreated dental patients with benign oral tumors, oral carcinoma, or periodontal disease. These results show that higher levels of immunoglobulin class-specific antibodies to HSV-1, the three adenoviruses, or Candida albicans are not a consistent finding in sera from patients with oral cancer when comparisons are made with healthy patients and patients with other oral diseases.
通过固相放射免疫测定法测定的未经治疗的健康牙科患者血清中针对1型单纯疱疹病毒（HSV-1）、5型、21型和31型人腺病毒以及白色念珠菌的免疫球蛋白类特异性抗体水平，与患有良性口腔肿瘤、口腔癌或牙周病的未经治疗的牙科患者血清中这些抗体的水平没有显著差异。这些结果表明，当与健康患者和患有其他口腔疾病的患者进行比较时，口腔癌患者血清中针对HSV-1、三种腺病毒或白色念珠菌的免疫球蛋白类特异性抗体水平升高并非一致的发现。
