Franceschi M, Truci G, Comi G, Lozza L, Marchettini P, Galardi G, Smirne S
J Neurol Neurosurg Psychiatry. 1984 Oct;47(10):1134-7. doi: 10.1136/jnnp.47.10.1134.
In randomly selected chronic alcoholics hospitalised for the first time for detoxification a high prevalence (68%) of cognitive deficits was found. Peripheral neuronal damage was seen in 74%, autonomic neuronal damage in 24%. Cognitive deficits were not correlated with age, daily ethanol intake, duration of alcohol abuse or severity of liver damage. There was no correlation of peripheral, autonomic and central nervous system damage. Alcohol-induced damage of the nervous system is a common complication of chronic alcoholism, whose clinical importance often obscures possible concomitant liver damage.
在首次因戒酒而住院的随机选取的慢性酒精中毒患者中,发现认知缺陷的患病率很高(68%)。74%的患者出现外周神经元损伤,24%出现自主神经元损伤。认知缺陷与年龄、每日乙醇摄入量、酒精滥用持续时间或肝损伤严重程度无关。外周、自主和中枢神经系统损伤之间没有相关性。酒精引起的神经系统损伤是慢性酒精中毒的常见并发症,其临床重要性常常掩盖了可能伴随的肝损伤。