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Mouse kidney renin gene is on chromosome one.

作者信息

Chirgwin J M, Schaefer I M, Diaz J A, Lalley P A

出版信息

Somat Cell Mol Genet. 1984 Nov;10(6):633-7. doi: 10.1007/BF01535229.

Abstract

The structural gene for mouse kidney renin (Ren-1) was localized to chromosome 1 by Southern blot analysis of mouse-hamster somatic cell hybrids with a cloned mouse submandibular renin cDNA probe. The submandibular renin gene (Ren-2) also lies on chromosome 1; so it may be, in those mouse lines which carry it, a tandem duplication of the kidney-type Ren-1 gene.

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