Gneditskaia E V, Bukhova V P, Beletskaia L V, Zakharova N A, Shakhanina K L
Biull Eksp Biol Med. 1984 Nov;98(11):586-9.
It was established by indirect immunofluorescence with the use of antibodies to human lactoferrin that thymic lymphocytes bear lactoferrin receptors in the point structures on the cell surface. The ability of thymic lymphocytes to express lactoferrin receptors depends on the cAMP concentration in the cell, inasmuch the treatment of lymphocytes with adenosine and theophylline increases the number of cells bearing lactoferrin receptors. Supernatant of thymic lymphocytes is also capable of stimulating expression of lactoferrin receptors. It is assumed that these treatments can be used for increasing the number of lymphocytes with lactoferrin receptors with the purpose of separation and study of the function of this subpopulation in health and in different pathological conditions.
利用抗人乳铁蛋白抗体通过间接免疫荧光法证实，胸腺淋巴细胞在细胞表面的点状结构上带有乳铁蛋白受体。胸腺淋巴细胞表达乳铁蛋白受体的能力取决于细胞内的环磷酸腺苷（cAMP）浓度，因为用腺苷和茶碱处理淋巴细胞会增加带有乳铁蛋白受体的细胞数量。胸腺淋巴细胞的上清液也能够刺激乳铁蛋白受体的表达。据推测，这些处理方法可用于增加带有乳铁蛋白受体的淋巴细胞数量，以便分离和研究该亚群在健康和不同病理状态下的功能。
