Walsh D E, Yaghoubian V, Behforooz A
Int J Obes. 1984;8(4):289-93.
An eight-week double-blind trial was conducted to test purified glucomannan fiber as a food supplement in 20 obese subjects. Glucomannan fiber (from konjac root) or placebo was given in 1-g doses (two 500 mg capsules) with 8 oz water, 1 h prior to each of three meals per d. Subjects were instructed not to change their eating or exercise patterns. Results showed a significant mean weight loss (5.5 lbs) using glucomannan over an eight-week period. Serum cholesterol and low-density lipoprotein cholesterol were significantly reduced (21.7 and 15.0 mg/dl respectively) in the glucomannan treated group. No adverse reactions to glucomannan were reported.
进行了一项为期八周的双盲试验，以测试纯化的葡甘露聚糖纤维作为食品补充剂对20名肥胖受试者的效果。每天三餐前1小时，给予葡甘露聚糖纤维（来自魔芋根）或安慰剂，剂量为1克（两粒500毫克胶囊），并用8盎司水冲服。受试者被要求保持其饮食和运动模式不变。结果显示，在八周时间内，使用葡甘露聚糖的受试者平均体重显著减轻（5.5磅）。葡甘露聚糖治疗组的血清胆固醇和低密度脂蛋白胆固醇显著降低（分别降低21.7和15.0毫克/分升）。未报告对葡甘露聚糖的不良反应。
