Wolf G, Schütte M, Römhild W
Neurosci Lett. 1984 Oct 12;51(2):277-80. doi: 10.1016/0304-3940(84)90564-0.
The uptake ratio of 65zinc into the postnatally developing hippocampal formation, cerebellum and remainder of the brain showed only minor differences, whilst following subcellular fractionation a marked decrease in 65zinc uptake from postnatal day 15 to adulthood was found in nuclear sediments (hippocampal formation 44.3%, cerebellum 27.5%), along with an increase in synaptosomal fractions on the hippocampal formation by 55.4% and of the cerebellum by 37.1%. The shift of zinc out of the perikarya into terminal fields during the postnatal development without substantial alterations of the net zinc content is supposed to be a consequence of a functional relation of zinc to synaptic transmission processes.
出生后发育阶段，65锌在海马结构、小脑及脑的其余部分的摄取率仅显示出微小差异，而在亚细胞分级分离后发现，从出生后第15天到成年期，核沉积物中65锌的摄取显著减少（海马结构减少44.3%，小脑减少27.5%），同时海马结构突触体部分增加了55.4%，小脑增加了37.1%。出生后发育过程中锌从胞体转移到终末区域，而锌的净含量没有实质性改变，这被认为是锌与突触传递过程功能关系的结果。
