Kalinowski M, Wolf G, Markefski M
Acta Histochem. 1983;73(1):33-40. doi: 10.1016/S0065-1281(83)80072-5.
Zinc was determined by means of atomic absorption techniques in the hippocampal formation, the cerebellum, the whole brain, and their subcellular fractions during the postnatal development of rats. Large quantities of zinc were found already in newborn animals. In the whole brain, the zinc amounts increased between the birth and the 15th day of age, whereas in the hippocampal formation and cerebellum the zinc concentration did not change remarkably during the postnatal maturation. The zinc content of the subcellular fractions revealed a shift to the synaptosomes and mitochondria during the postnatal development. No significant difference of zinc amounts was shown between the CA3 and hilus fasciae dentatae region and the whole hippocampal formation. Concluding from the present results there are obvious discrepancies between the quantitative and histochemical data of the zinc distribution in the rat brain.
在大鼠出生后的发育过程中，采用原子吸收技术测定了海马结构、小脑、全脑及其亚细胞组分中的锌含量。在新生动物中就已发现大量锌。在全脑中，锌含量在出生至15日龄之间增加，而在海马结构和小脑中，锌浓度在出生后成熟过程中没有显著变化。亚细胞组分的锌含量显示，在出生后的发育过程中，锌向突触体和线粒体转移。CA3区和齿状回门区与整个海马结构之间的锌含量没有显著差异。根据目前的结果推断，大鼠脑中锌分布的定量和组织化学数据存在明显差异。
