Quinn J H, Kent J N
Oral Surg Oral Med Oral Pathol. 1984 Nov;58(5):511-21. doi: 10.1016/0030-4220(84)90071-9.
Animal studies were carried out to determine a simple technique of implantation of nonresorbable polycrystalline hydroxylapatite solid root forms and the biocompatibility of the material placed in fresh extraction sockets. An appropriately shaped root form was evaluated, and alveolar bone preservation was investigated in dogs and primates. It was found that bone and soft tissue would migrate across the HA root implant when placed 2 to 3 mm below the alveolar bone crest without soft-tissue closure. It was not necessary to use roots that fit the socket from the apex to the alveolar crest. An average of 2 mm more alveolar bone was preserved in fresh extraction sites as compared to control sites. The results of the animal studies indicated the appropriateness of a clinical trial in human beings.
进行动物研究以确定不可吸收多晶羟基磷灰石实心牙根形态的简单植入技术以及置于新鲜拔牙窝内材料的生物相容性。评估了形状合适的牙根形态，并在犬和灵长类动物中研究了牙槽骨保存情况。结果发现，当将HA牙根植入物置于牙槽嵴下方2至3毫米且不进行软组织封闭时，骨和软组织会跨过该植入物迁移。无需使用从根尖到牙槽嵴都与牙槽窝适配的牙根。与对照部位相比，新鲜拔牙部位平均多保留了2毫米的牙槽骨。动物研究结果表明在人类中进行临床试验是合适的。
