Krishnan Vidya, Lakshmi T
Professor and Head of the Department of Oral Medicine and Radiology, SRM Kattankulathur Dental College and Hospitals, Chennai, India.
J Adv Pharm Technol Res. 2013 Apr;4(2):78-83. doi: 10.4103/2231-4040.111523.
Advancement of materials technology has been immense, especially in the past 30 years. Ceramics has not been new to dentistry. Porcelain crowns, silica fillers in composite resins, and glass ionomer cements have already been proved to be successful. Materials used in the replacement of tissues have come a long way from being inert, to compatible, and now regenerative. When hydroxyapatite was believed to be the best biocompatible replacement material, Larry Hench developed a material using silica (glass) as the host material, incorporated with calcium and phosphorous to fuse broken bones. This material mimics bone material and stimulates the regrowth of new bone material. Thus, due to its biocompatibility and osteogenic capacity it came to be known as "bioactive glass-bioglass." It is now encompassed, along with synthetic hydroxyapatite, in the field of biomaterials science known as "bioactive ceramics." The aim of this article is to give a bird's-eye view, of the various uses in dentistry, of this novel, miracle material which can bond, induce osteogenesis, and also regenerate bone.
材料技术的进步是巨大的，尤其是在过去30年里。陶瓷在牙科领域并不陌生。烤瓷冠、复合树脂中的二氧化硅填料以及玻璃离子水门汀已被证明是成功的。用于组织替代的材料已经走过了漫长的道路，从惰性材料发展到相容性材料，现在又发展到再生材料。当羟基磷灰石被认为是最佳的生物相容性替代材料时，拉里·亨奇开发了一种以二氧化硅（玻璃）为主材料的材料，并加入钙和磷以融合骨折部位。这种材料模仿骨材料并刺激新骨材料的再生。因此，由于其生物相容性和成骨能力，它被称为“生物活性玻璃——生物玻璃”。现在，它与合成羟基磷灰石一起，被纳入生物材料科学领域中被称为“生物活性陶瓷”的范畴。本文旨在鸟瞰这种新型的神奇材料在牙科的各种用途，它能够粘结、诱导成骨并且再生骨骼。
