Eandi M, Buraglio M, Arduino C, Viano I, Sansalvadore G, Arbinolo M A
Int J Clin Pharmacol Res. 1984;4(5):349-54.
In this study the authors' purpose was to observe the effects of surgical stress on the number of lymphocyte beta-adrenergic receptors in hypertensive and normotensive subjects. It was noticed that after surgery a significant reduction occurred in the number of binding sites of lymphocytes of both hypertensive and normotensive subjects. The time course of recovery to the pre-operative values of binding sites varied between the two groups, being slower in normotensive than in hypertensive patients. This might suggest a different pattern of regulation of the beta-adrenergic receptor between hypertensive and normotensive subjects.
在本研究中，作者的目的是观察手术应激对高血压患者和血压正常者淋巴细胞β-肾上腺素能受体数量的影响。研究发现，手术后高血压患者和血压正常者淋巴细胞的结合位点数量均显著减少。两组患者结合位点恢复到术前值的时间进程有所不同，血压正常者比高血压患者恢复得慢。这可能提示高血压患者和血压正常者β-肾上腺素能受体的调节模式不同。
