Niechaj A, Lzóg M
Arch Int Physiol Biochim. 1976 Feb;84(1):99-104. doi: 10.3109/13813457609072351.
The effect of changes in duration of the conditioning tetanus on the size of the testing depressor response was studied in rabbits anaesthetized with urethane. Depressor responses were evoked by stimulation of the aortic nerve. The interval between the conditioning and testing stimulation was fixed at 40 and 120 sec. Two frequencies of conditioning tetanus were employed. Brief conditioning tetani facilitate the testing response. With lengthening of the conditioning stimulation the size of the testing response is decreased and when duration of the conditioning amounts to 20-60 sec depression of the testing fall of blood pressure reaches a steady level. Further increase in duration of the conditioning tetanus to 180 sec does not affect the plateau of depression of the testing response. The longest duration of conditioning affecting the size of the testing response is considered to determine the range of control of the testing response exerted by preceding conditioning tetanus. Since the levels of plateau of depression are different for two used frequencies of conditioning, it is suggested that this factor may control the size of the testing response beyond the range of control executed by the duration of the conditioning tetanus.
在用氨基甲酸乙酯麻醉的家兔中，研究了条件强直刺激持续时间的变化对测试降压反应大小的影响。通过刺激主动脉神经诱发降压反应。条件刺激和测试刺激之间的间隔固定为40秒和120秒。采用了两种频率的条件强直刺激。短暂的条件强直刺激可促进测试反应。随着条件刺激时间的延长，测试反应的大小减小，当条件刺激持续时间达到20 - 60秒时，测试血压下降的抑制达到稳定水平。条件强直刺激持续时间进一步增加到180秒，并不影响测试反应抑制的平台期。影响测试反应大小的最长条件刺激持续时间被认为决定了先前条件强直刺激对测试反应的控制范围。由于两种使用的条件刺激频率的抑制平台水平不同，提示该因素可能在条件强直刺激持续时间所执行的控制范围之外控制测试反应的大小。
