Nadiger H A, Rao A S, Sadasivudu B
Int J Vitam Nutr Res. 1984;54(4):307-11.
Vitamin E is known to have an interaction with pyridoxine. To understand the functional significance of this interaction a study was carried out on the effect of simultaneous administration of vitamin E and pyridoxine on erythrocyte membrane Na+K+ ATPase activity. Adult male volunteers belonging to low socio-economic class with prior consent were used as subjects for the study. The results of the study have shown that administration of vitamin E alone brings about a transient increase in the total and ouabain insensitive Na+K+ ATPase. Administration of B6 along with vitamin E brought about an increase in the total and true Na+K+ ATPase activity. B6 administration alone showed a statistically insignificant increase in true ATPase activity. The results of the study are interpreted to show that administration of vitamin E along with B6 is beneficial to membrane function.
众所周知，维生素E与吡哆醇存在相互作用。为了解这种相互作用的功能意义，开展了一项关于同时给予维生素E和吡哆醇对红细胞膜钠钾ATP酶活性影响的研究。研究对象为事先征得同意的低社会经济阶层成年男性志愿者。研究结果表明，单独给予维生素E会使总钠钾ATP酶和哇巴因不敏感钠钾ATP酶出现短暂升高。同时给予维生素E和B6会使总钠钾ATP酶和真性钠钾ATP酶活性升高。单独给予B6时，真性ATP酶活性虽有升高，但在统计学上无显著意义。该研究结果表明，同时给予维生素E和B6对膜功能有益。
