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成骨样细胞合成胶原酶。

Collagenase synthesis by osteoblast-like cells.

作者信息

Otsuka K, Sodek J, Limeback H F

出版信息

Calcif Tissue Int. 1984 Dec;36(6):722-4. doi: 10.1007/BF02405395.

DOI:10.1007/BF02405395
PMID:6099212
Abstract

Cultures of osteoblast-like cells from a rat sarcoma and osteoblast-enriched populations of rat calvarial cells synthesize and secrete a true collagenase and collagenase inhibitor. The enzyme, which is produced in a latent form, appears to be similar to the enzyme produced by fibroblasts.

摘要

来自大鼠肉瘤的成骨细胞样细胞培养物以及富含成骨细胞的大鼠颅骨细胞群体能够合成并分泌一种真正的胶原酶和胶原酶抑制剂。这种以潜伏形式产生的酶似乎与成纤维细胞产生的酶相似。

相似文献

1
Collagenase synthesis by osteoblast-like cells.成骨样细胞合成胶原酶。
Calcif Tissue Int. 1984 Dec;36(6):722-4. doi: 10.1007/BF02405395.
2
Synthesis of collagenase and collagenase inhibitors by osteoblast-like cells in culture.培养的成骨样细胞合成胶原酶和胶原酶抑制剂。
Eur J Biochem. 1984 Nov 15;145(1):123-9. doi: 10.1111/j.1432-1033.1984.tb08530.x.
3
[Effect of PTH and periodic tension on osteoblast-like cells for collagenase synthesis].
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Osteoblast collagenase: collagenase synthesis by clonally derived mouse osteogenic (MC3T3-E1) cells.
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Monensin inhibits collagenase production in osteoblastic cell cultures and also inhibits both collagenase release and bone resorption in mouse calvaria cultures.莫能菌素抑制成骨细胞培养物中胶原酶的产生，并且还抑制小鼠颅骨培养物中胶原酶的释放和骨吸收。
Biochem Int. 1985 Sep;11(3):273-80.
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The effect of lipopolysaccharide from bacteroides gingivalis and muramyl dipeptide on osteoblast collagenase release.
Calcif Tissue Int. 1989 May;44(5):361-3. doi: 10.1007/BF02556318.
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Mouse osteoblasts synthesize collagenase in response to bone resorbing agents.小鼠成骨细胞会响应骨吸收剂而合成胶原酶。
Biochim Biophys Acta. 1984 Nov 6;802(1):151-4. doi: 10.1016/0304-4165(84)90046-1.
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Stimulation of collagenase production by rat osteosarcoma cells can occur in a subpopulation of cells.大鼠骨肉瘤细胞产生胶原酶的刺激作用可能发生在细胞亚群中。
J Bone Miner Res. 1990 Sep;5(9):963-71. doi: 10.1002/jbmr.5650050910.
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Initial characterization of a neutral metalloproteinase, active on native 3/4-collagen fragments, synthesized by ROS 17/2.8 osteoblastic cells, periodontal fibroblasts, and identified in gingival crevicular fluid.对一种中性金属蛋白酶的初步特性研究，该酶对天然3/4型胶原片段有活性，由ROS 17/2.8成骨细胞、牙周成纤维细胞合成，并在龈沟液中被鉴定出来。
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Mineralization induced by beta-glycerophosphate in cultures leads to a marked increase in collagenase synthesis by mouse osteogenic MC3T3-E1 cells under subsequent stimulation with heparin.
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引用本文的文献

1
Phagocytosis of different matrix components by different cell types at bone-forming sites in cultured mouse calvariae.培养的小鼠颅骨中成骨部位不同细胞类型对不同基质成分的吞噬作用。
Cell Tissue Res. 1986;245(1):9-17. doi: 10.1007/BF00218081.

本文引用的文献

1
Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma.来自大鼠骨肉瘤的甲状旁腺激素反应性克隆细胞系。
Endocrinology. 1980 Nov;107(5):1494-503. doi: 10.1210/endo-107-5-1494.
2
Human skin fibroblast collagenase inhibitor. Purification and biochemical characterization.人皮肤成纤维细胞胶原酶抑制剂。纯化及生化特性分析。
J Biol Chem. 1983 Oct 25;258(20):12252-8.
3
Con A stimulation of collagenase synthesis by human gingival fibroblasts.刀豆球蛋白A对人牙龈成纤维细胞胶原酶合成的刺激作用。
J Periodontal Res. 1983 Mar;18(2):149-55. doi: 10.1111/j.1600-0765.1983.tb00347.x.
4
Human skin fibroblast procollagenase: mechanisms of activation by organomercurials and trypsin.人皮肤成纤维细胞原胶原酶：有机汞化合物和胰蛋白酶的激活机制。
Biochemistry. 1983 Jan 4;22(1):61-8. doi: 10.1021/bi00270a009.
5
Synthesis of collagen, collagenase and collagenase inhibitors by cloned human gingival fibroblasts and the effect of concanavalin A.克隆的人牙龈成纤维细胞合成胶原蛋白、胶原酶及胶原酶抑制剂以及伴刀豆球蛋白A的作用
Biochem Biophys Res Commun. 1982 Jul 16;107(1):357-66. doi: 10.1016/0006-291x(82)91712-0.
6
Isolation of bone cell clones with differences in growth, hormone responses, and extracellular matrix production.分离具有生长、激素反应和细胞外基质产生差异的骨细胞克隆。
J Cell Biol. 1982 Feb;92(2):452-61. doi: 10.1083/jcb.92.2.452.
7
A highly sensitive and specific assay for vertebrate collagenase.一种用于检测脊椎动物胶原酶的高灵敏度和高特异性检测方法。
J Periodontal Res. 1981 Jul;16(4):425-33. doi: 10.1111/j.1600-0765.1981.tb00993.x.
8
Uptake of collagenolytic enzymes by bone cells during isolation from embryonic rat calvaria.从胚胎大鼠颅骨分离过程中骨细胞对胶原分解酶的摄取。
Calcif Tissue Int. 1981;33(3):255-60. doi: 10.1007/BF02409446.
9
Collagenolytic enzymes and their naturally occurring inhibitors.
Int Rev Connect Tissue Res. 1981;9:151-90. doi: 10.1016/b978-0-12-363709-3.50010-3.
10
Mouse bone collagenase. The effect of heparin on the amount of enzyme released in tissue culture and on the activity of the enzyme.
Calcif Tissue Res. 1973;12(3):247-58. doi: 10.1007/BF02013739.