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偏头痛患者中阿片类和5-羟色胺能系统的神经内分泌学研究。

Neuroendocrinological study of opioid and serotoninergic systems in migraine patients.

作者信息

Bussone G, Boiardi A, La Mantia L, Frediani F, Martini A, Di Giulio A M, Panerai A E

出版信息

Ital J Neurol Sci. 1984 Dec;5(4):413-6. doi: 10.1007/BF02042625.

DOI:10.1007/BF02042625
PMID:6099346
Abstract

PRL response to morphine in a group of migraine subjects was studied in the baseline condition and after neuroendocrinological inhibition and stimulation tests. No significant differences were found in comparison with control subjects. This demonstrated the integrity of the opioid system and serotoninergic pathways in migraine subjects.

摘要

在一组偏头痛患者中，研究了在基线状态下以及神经内分泌抑制和刺激试验后催乳素对吗啡的反应。与对照受试者相比，未发现显著差异。这证明了偏头痛患者中阿片系统和5-羟色胺能通路的完整性。

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Neuroendocrinological study of opioid and serotoninergic systems in migraine patients.偏头痛患者中阿片类和5-羟色胺能系统的神经内分泌学研究。
Ital J Neurol Sci. 1984 Dec;5(4):413-6. doi: 10.1007/BF02042625.
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本文引用的文献

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Effects of methergoline on central monoamine neurones. Evidence for a selective blockade of central 5-HT receptors.麦角新碱对中枢单胺能神经元的作用。中枢5-羟色胺受体选择性阻断的证据。
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Characterization of ergot and non-ergot serotonin antagonists by prolactin and growth hormone profiles during wakefulness and sleep.通过清醒和睡眠期间的催乳素和生长激素谱对麦角和非麦角血清素拮抗剂进行表征。
Brain Res. 1980 Dec 8;202(2):357-63. doi: 10.1016/0006-8993(80)90147-x.
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Role of central nervous system neurotransmitters in mediating the effects of morphine on growth hormone- and prolactin-secretion in the rat.
中枢神经系统神经递质在介导吗啡对大鼠生长激素和催乳素分泌影响中的作用。
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1-Methyl-8-beta-carbobenzyloxy-aminomethyl-10-alpha-ergoline, a potent and long-lasting 5-hydroxytryptamine antagonist.1-甲基-8-β-苄氧羰基-氨甲基-10-α-麦角灵，一种强效且长效的5-羟色胺拮抗剂。
Nature. 1965 Jul 24;207(995):421-2. doi: 10.1038/207421a0.
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Slight effect of L-tryptophan on growth hormone release in normal human subjects.L-色氨酸对正常人体生长激素释放的轻微影响。
J Clin Endocrinol Metab. 1974 Jul;39(1):1-5. doi: 10.1210/jcem-39-1-1.
6
Effect of 5-hydroxytryptophan (5-HTP) on growth hormone and ACTH release in man.
J Clin Endocrinol Metab. 1973 Jan;36(1):204-6. doi: 10.1210/jcem-36-1-204.
7
5-hydroxytryptamine supersensitivity as a new theory of headache and central pain: a clinical pharmacological approach with p-chlorophenylalanine.5-羟色胺超敏反应作为头痛和中枢性疼痛的新理论：对氯苯丙氨酸的临床药理学研究方法
Psychopharmacologia. 1973;29(4):347-56. doi: 10.1007/BF00429282.
8
Inhibitory effect of an ergoline derivative, methergoline, on growth hormone and prolactin levels in acromegalic patients.麦角新碱（一种麦角灵衍生物）对肢端肥大症患者生长激素和催乳素水平的抑制作用。
J Clin Endocrinol Metab. 1976 Aug;43(2):356-63. doi: 10.1210/jcem-43-2-356.
9
Effects of naloxone, morphine and methionine enkephalin on serum prolactin, luteinizing hormone, follicle stimulating hormone, thyroid stimulating hormone and growth hormone.纳洛酮、吗啡和甲硫氨酸脑啡肽对血清催乳素、黄体生成素、卵泡刺激素、促甲状腺激素和生长激素的影响。
Life Sci. 1977 Aug 1;21(3):461-6. doi: 10.1016/0024-3205(77)90528-8.
10
Morphine alters distribution of GABA in thalamus.吗啡改变丘脑γ-氨基丁酸的分布。
Brain Res. 1977 Mar 25;124(2):373-8. doi: 10.1016/0006-8993(77)90896-4.