Maruyama Y, Chin H W, Young A B, Beach J, Tibbs P, Goldstein S, Markesbery W
J Neurooncol. 1984;2(4):349-60. doi: 10.1007/BF00178118.
Magnetic resonance (MR) imaging of the brain allows very effective localization of tumor in brain, visualization of brain reaction to tumor, peritumoral edema, as well as destruction of normal anatomy and spread of tumor. MR readily imaged the brain in multiple views allowing three dimensional (3D) evaluation and more precise localization of tumor in the depths of the brain. It also assessed the extent of tumor infiltration away from the primary site. In an ongoing study of Cf-252 neutron brachytherapy of hemispheric malignant gliomas of the brain, we have found that the extent of tumor and the planning of the placement of multiple applicators in the brain for implant therapy was facilitated by both CT and MR scanning, but MR allowed better 3D localization, assessment of response and follow-up of tumor response. MR gave additional and different types of information about the tumor than CT scanning based upon proton distribution which greatly aided planning of tumor implant therapy and understanding of patterns of tumor response and recurrence after therapy.
脑部磁共振成像（MR）能够非常有效地定位脑部肿瘤，显示脑部对肿瘤的反应、瘤周水肿，以及正常解剖结构的破坏和肿瘤的扩散情况。MR可以从多个角度对脑部进行成像，从而实现三维（3D）评估，并更精确地定位脑部深处的肿瘤。它还能评估肿瘤从原发部位向外浸润的程度。在一项关于 Cf-252 中子近距离治疗脑部半球恶性胶质瘤的正在进行的研究中，我们发现，CT 和 MR 扫描都有助于确定肿瘤范围以及规划脑部多个施源器的植入治疗位置，但 MR 能实现更好的 3D 定位、评估肿瘤反应以及对肿瘤反应进行随访。基于质子分布，MR 提供了与 CT 扫描不同的有关肿瘤的额外信息类型，这极大地有助于肿瘤植入治疗的规划以及理解治疗后肿瘤反应和复发模式。
