Torre D, Maggiolo F, Sampietro C
Chemioterapia. 1984 Aug;3(4):255-7.
Forty children with pertussis were treated in a randomized trial with josamycin or erythromycin. The pathogen was isolated in 15 cases by immunofluorescent antibody (IFA) technique. The clinical response of both groups was good and comparable. A 15-day course of therapy was able to eradicate the pathogen in all but one patient. Three patients showed minor side effects: diarrhea (2), rash (1).
40名百日咳患儿参与了一项关于交沙霉素或红霉素的随机试验。通过免疫荧光抗体(IFA)技术在15例中分离出病原体。两组的临床反应良好且相当。15天的疗程能够根除除1例患者外的所有病原体。3例患者出现轻微副作用:腹泻(2例)、皮疹(1例)。