Kloetzel K, Chieffi P P, Faleiros J J, Filho T J
Trop Geogr Med. 1977 Dec;29(4):407-10.
Inocula of S. mansoni and T. gondii well tolerated by albino mice when given singly, were given concomitantly to groups of animals. Few notable effects were observed when toxoplasmosis preceded schistosomiasis, but the S. mansoni leads to T. gondii model, with an interval of 59 days between infections, led to massive mortality, great weight loss and a striking splenomegaly. These findings are very similar to data from previous work on the S. mansoni leads to Trypanosoma cruzi model. The authors believe that other examples of such a type of potentialization should be searched for in human schistosomiasis also.
单独给予曼氏血吸虫和刚地弓形虫接种物时，白化小鼠耐受性良好，现将这两种接种物同时给予几组动物。当弓形虫病先于血吸虫病发生时，未观察到明显影响，但在血吸虫病导致弓形虫病的模型中，两次感染间隔59天，导致大量死亡、体重显著减轻和脾脏明显肿大。这些发现与之前关于血吸虫病导致克氏锥虫病模型的研究数据非常相似。作者认为，在人类血吸虫病中也应寻找这种潜在增强作用的其他例子。
