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2
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The CD8 T cell response to staphylococcal enterotoxins.
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2
Delayed hypersensitivity-type granuloma formation and dermal reaction induced and elicited by a soluble factor isolated from Schistosoma mansoni eggs.由从曼氏血吸虫卵中分离出的一种可溶性因子诱导并引发的迟发型超敏反应型肉芽肿形成和皮肤反应。
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Anti-L3T4 antibody treatment suppresses hepatic granuloma formation and abrogates antigen-induced interleukin-2 production in Schistosoma mansoni infection.抗L3T4抗体治疗可抑制曼氏血吸虫感染中肝脏肉芽肿的形成，并消除抗原诱导的白细胞介素-2产生。
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The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent.四种小鼠白细胞介素-5特异性单克隆抗体的特性鉴定及小鼠和人白细胞介素-5酶联免疫吸附测定法的开发
J Immunol. 1988 Sep 1;141(5):1576-81.
5
Eggs of Schistosoma mansoni stimulate endothelial cell proliferation in vitro.曼氏血吸虫卵在体外刺激内皮细胞增殖。
J Infect Dis. 1988 Sep;158(3):556-62. doi: 10.1093/infdis/158.3.556.
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Regulation of granulomatous inflammation in murine schistosomiasis. IV. Antigen-induced suppressor T cells down-regulate proliferation and IL-2 production.小鼠血吸虫病中肉芽肿性炎症的调节。IV. 抗原诱导的抑制性T细胞下调增殖和白细胞介素-2的产生。
J Immunol. 1990 Aug 15;145(4):1257-64.
7
Clonal expansion precedes anergy and death of V beta 8+ peripheral T cells responding to staphylococcal enterotoxin B in vivo.在体内对葡萄球菌肠毒素B作出反应的Vβ8 +外周T细胞出现无反应性和死亡之前，会发生克隆性扩增。
Eur J Immunol. 1991 Aug;21(8):1963-6. doi: 10.1002/eji.1830210827.
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Superantigens: mechanism of T-cell stimulation and role in immune responses.超抗原：T细胞刺激机制及其在免疫反应中的作用
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9
Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni.曼氏血吸虫这种寄生性蠕虫诱导Th2反应时，Th1细胞因子产生会下调。
J Exp Med. 1991 Jan 1;173(1):159-66. doi: 10.1084/jem.173.1.159.
10
Dynamic analysis of splenic Th1 and Th2 lymphocyte functions in mice infected with Schistosoma japonicum.日本血吸虫感染小鼠脾脏Th1和Th2淋巴细胞功能的动态分析
Infect Immun. 1991 Sep;59(9):2934-40. doi: 10.1128/iai.59.9.2934-2940.1991.

曼氏血吸虫免疫反应期间CD4 + T细胞受体Vβ的使用情况。

CD4+ T-cell receptor V beta usage during the immune response to Schistosoma mansoni.

作者信息

Vella A T, Pearce E J

机构信息

Department of Microbiology, Immunology and Parasitology, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853-6401.

出版信息

Infect Immun. 1993 Dec;61(12):5381-3. doi: 10.1128/iai.61.12.5381-5383.1993.

DOI:10.1128/iai.61.12.5381-5383.1993
PMID:7901168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC281325/
Abstract

T-cell receptor V beta usage by CD4+ cells during the immune response of C57BL/6J mice to Schistosoma mansoni was examined. During acute infection, the distribution of splenic CD4+ cells utilizing V beta s 3, 5, 6, 7, 8.1/8.2, 9, and 11 was not significantly different from that in uninfected mice. Preferential V beta usage or deletion was not detected when either the primary or the memory immune response to parasite eggs was examined.

摘要

研究了C57BL/6J小鼠对曼氏血吸虫免疫应答过程中CD4+细胞的T细胞受体Vβ使用情况。在急性感染期间，利用Vβ3、5、6、7、8.1/8.2、9和11的脾CD4+细胞分布与未感染小鼠无显著差异。在检测对寄生虫卵的初次或记忆免疫应答时，未检测到Vβ的优先使用或缺失。