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Effect of cholecystokinin octapeptide on ethanol intake in the rat.

作者信息

Kulkosky P J

出版信息

Alcohol. 1984 Mar-Apr;1(2):125-8. doi: 10.1016/0741-8329(84)90067-3.

DOI:10.1016/0741-8329(84)90067-3
PMID:6100356
Abstract

Water-deprived rats received 3%, 6% or 9% ethanol solution or water for 30 min daily. Intraperitoneal injection of cholecystokinin octapeptide (CCK-8, 2.0-4.0 micrograms/kg) significantly and specifically inhibited ethanol intake. The findings are consistent with previous reports of specificity of the inhibition of caloric intake by CCK-8. Administration of CCK-8 may influence ethanol intake by modulating a satiety signal that ordinarily controls ethanol intake.

摘要

相似文献

1
Effect of cholecystokinin octapeptide on ethanol intake in the rat.
Alcohol. 1984 Mar-Apr;1(2):125-8. doi: 10.1016/0741-8329(84)90067-3.
2
Sulphated cholecystokinin octapeptide inhibits ethanol consumption in the rat.硫酸化胆囊收缩素八肽抑制大鼠的乙醇摄取。
Alcohol. 1984 Sep-Oct;1(5):409-12. doi: 10.1016/0741-8329(84)90012-0.
3
Cholecystokinin and satiation with alcohol.胆囊收缩素与酒精饱腹感
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Cholecystokinin octapeptide reduces ethanol intake in food- and water-sated rats.胆囊收缩素八肽可减少食物和水充足的大鼠的乙醇摄入量。
Pharmacol Biochem Behav. 1990 Feb;35(2):493-5. doi: 10.1016/0091-3057(90)90193-l.
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Cholecystokinin-induced satiation with ethanol: effects of lighting cycle and limited access procedures.胆囊收缩素诱导的乙醇饱腹感：光照周期和有限摄入程序的影响
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Bombesin and litorin inhibit ethanol intake.蛙皮素和促胃液素释放肽抑制乙醇摄入。
Peptides. 1985;6 Suppl 2:103-5. doi: 10.1016/0196-9781(85)90141-x.
7
Cholecystokinin and bombesin inhibit ethanol and food intake in rats selectively bred for ethanol sensitivity.缩胆囊素和蛙皮素可抑制对乙醇敏感的选择性培育大鼠的乙醇摄入和食物摄取。
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MK-329 blocks the inhibition of alcohol intake by CCK-8.
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Cholecystokinin interacts with prefeeding to impair runway performance.
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Systemic administration of cholecystokinin (CCK) inhibits operant water intake in rats: implications for the CCK-satiety hypothesis.
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