孕前补充维生素可能预防神经管缺陷。
Possible prevention of neural-tube defects by periconceptional vitamin supplementation.
作者信息
Smithells R W, Sheppard S, Schorah C J, Seller M J, Nevin N C, Harris R, Read A P, Fielding D W
出版信息
Lancet. 1980 Feb 16;1(8164):339-40. doi: 10.1016/s0140-6736(80)90886-7.
PMID:6101792
Abstract
Women who had previously given birth to one or more infants with a neural-tube defect (NTD) were recruited into a trial of periconceptional multivitamin supplementation. 1 of 178 infants/fetuses of fully supplemented mothers (0.6%) had an NTD, compared with 13 of 260 infants/fetuses of unsupplemented mothers (5.0%).
摘要
之前生育过一个或多个神经管缺陷（NTD）婴儿的女性被招募到一项围孕期补充多种维生素的试验中。完全补充维生素的母亲所生的178名婴儿/胎儿中有1名（0.6%）患有神经管缺陷，而未补充维生素的母亲所生的260名婴儿/胎儿中有13名（5.0%）患有神经管缺陷。
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