Lamb R A, Choppin P W
Philos Trans R Soc Lond B Biol Sci. 1980 Feb 25;288(1029):327-33. doi: 10.1098/rstb.1980.0008.
A polypeptide with a molecular mass of ca. 11 000 has been found in various cell types infected with several strains of influenza A and B viruses. Differences have been found in the electrophoretic mobility of this polypeptide in cells infected with different strains, suggesting that it is virus coded. Peptide mapping studies have shown that this polypeptide is distinct from the eight defined influenza virus gene products. A fraction containing a virus-specific mRNA with an estimated size of ca. 300-400 nucleotides has been obtained. Schemes for the synthesis of this mRNA are discussed.
在感染了几种甲型和乙型流感病毒毒株的多种细胞类型中发现了一种分子量约为11000的多肽。在感染不同毒株的细胞中，已发现该多肽的电泳迁移率存在差异，这表明它是由病毒编码的。肽图谱研究表明，该多肽与八种已确定的流感病毒基因产物不同。已获得了一个含有估计大小约为300 - 400个核苷酸的病毒特异性mRNA的组分。讨论了该mRNA的合成方案。
