Ignatov S A, Burbaeva G Sh, Tsutsul'kovskaia M Ia, Abramova L I, Trubnikov V I
Zh Nevropatol Psikhiatr Im S S Korsakova. 1980;80(9):1331-7.
beta-endorphin concentration in cerebrospinal fluid (CSF) in 21 schizophrenic and 15 neurological patients was determined by radioimmune assay. On the basis of the obtained data a correlation between the change of beta-endorphin level in CSF of schizophrenics and that of the clinical state of these patients was assumed as a result of a short-term discontinuance of the treatment. It was established that the reduction of beta-endorphin level in CSF of schizophrenics correlates with the intensification of hallucinatory-delusional disorders.