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[人类血液和脑脊液中的β-内啡肽水平]

[Beta-endorphin levels in the blood and cerebrospinal fluid in humans].

作者信息

Radzikowska B, Szczudlik A, Lypka A

出版信息

Neurol Neurochir Pol. 1985 Jul-Aug;19(4):281-5.

PMID:2936969
Abstract

Beta-endorphin concentrations were determined in the cerebrospinal fluid and blood before and after lumbar tap in 19 patients with lumbosacral pains. No statistically significant difference was observed in this concentration before and after lumbar tap, although in individual cases a significant rise of beta-endorphin occurred. The mean beta-endorphin concentration in blood was about twice as high as in the cerebrospinal fluid. No correlation was noticed between the concentration of beta-endorphin in blood and in CSF.

摘要

对19例腰骶部疼痛患者在腰椎穿刺前后测定其脑脊液和血液中的β-内啡肽浓度。尽管个别病例中β-内啡肽有显著升高,但腰椎穿刺前后该浓度未观察到统计学上的显著差异。血液中β-内啡肽的平均浓度约为脑脊液中的两倍。血液和脑脊液中β-内啡肽的浓度之间未发现相关性。

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1
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引用本文的文献

1
Roles of β-Endorphin in Stress, Behavior, Neuroinflammation, and Brain Energy Metabolism.β-内啡肽在应激、行为、神经炎症和大脑能量代谢中的作用。
Int J Mol Sci. 2020 Dec 30;22(1):338. doi: 10.3390/ijms22010338.
2
Volume transmission of beta-endorphin via the cerebrospinal fluid; a review.β-内啡肽经脑脊液的容积传递;综述。
Fluids Barriers CNS. 2012 Aug 10;9(1):16. doi: 10.1186/2045-8118-9-16.