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胰岛:免疫细胞化学上不同细胞类型之间的染料偶联。

Islets of Langerhans: dye coupling among immunocytochemically distinct cell types.

作者信息

Michaels R L, Sheridan J D

出版信息

Science. 1981 Nov 13;214(4522):801-3. doi: 10.1126/science.6117129.

DOI:10.1126/science.6117129
PMID:6117129
Abstract

Cells in isolated rat islets of Langerhans were microinjected with Lucifer Yellow CH in a medium containing 16.7 millimolar glucose. Dye was rapidly transferred from the injected cell to neighboring islet cells without specificity with regard to the immunocytochemical identity of either the donor or the recipient cells. The transfer of dye between the islet cells (types A, B, and D) demonstrates homologous and heterologous cell coupling in a system where the normal proportions and relationships of the cell types are maintained.

摘要

在含有16.7毫摩尔葡萄糖的培养基中,将荧光黄CH显微注射到分离的大鼠胰岛细胞中。染料迅速从注射的细胞转移到相邻的胰岛细胞,对供体细胞或受体细胞的免疫细胞化学特性没有特异性。胰岛细胞(A、B和D型)之间的染料转移证明了在维持细胞类型正常比例和关系的系统中存在同源和异源细胞偶联。

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Islets of Langerhans: dye coupling among immunocytochemically distinct cell types.胰岛:免疫细胞化学上不同细胞类型之间的染料偶联。
Science. 1981 Nov 13;214(4522):801-3. doi: 10.1126/science.6117129.
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