HTLV: the virus of adult T-cell leukaemia in Japan and elsewhere.

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作者信息

Gallo R C, Blattner W A, Reitz M S, Ito Y

出版信息

Lancet. 1982 Mar 20;1(8273):683.

PMID:6121990

Abstract

摘要

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HTLV: the virus of adult T-cell leukaemia in Japan and elsewhere.

Lancet. 1982 Mar 20;1(8273):683.

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Foxp3-dependent transformation of human primary CD4+ T lymphocytes by the retroviral protein tax.逆转录病毒蛋白Tax通过Foxp3依赖的方式使人类原代CD4 + T淋巴细胞发生转化。

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Niclosamide, an anti-helminthic molecule, downregulates the retroviral oncoprotein Tax and pro-survival Bcl-2 proteins in HTLV-1-transformed T lymphocytes.氯硝柳胺，一种抗蠕虫分子，可下调人嗜T淋巴细胞病毒1型（HTLV-1）转化的T淋巴细胞中的逆转录病毒癌蛋白Tax和促生存Bcl-2蛋白。

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The discovery of the first human retrovirus: HTLV-1 and HTLV-2.第一种人类逆转录病毒的发现：人类嗜T淋巴细胞病毒1型（HTLV-1）和人类嗜T淋巴细胞病毒2型（HTLV-2）。

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