Chodera A, Konkiewicz B, Szczawiński R, Nowakowska E, Kozaryn I
Arch Immunol Ther Exp (Warsz). 1977;25(6):807-12.
Imipramine in doses of 0.35-0.45 mg/kg body weight usually induces a drop in arterial blood pressure; the drop is statistically significant in patients with essential hypertension. In these patients, a significant increase in excretion of catecholamines in urine was observed when compared with a control group. In both groups no changes in heart action were found.
按0.35 - 0.45毫克/千克体重的剂量服用丙咪嗪通常会导致动脉血压下降;在原发性高血压患者中,这种下降具有统计学意义。与对照组相比,这些患者尿中儿茶酚胺的排泄量显著增加。两组患者的心脏活动均未发现变化。