Stacpoole P W, Robertson D
South Med J. 1982 May;75(5):634-5. doi: 10.1097/00007611-198205000-00041.
Autonomic neuropathy occurs frequently in diabetic patients but is seldom effectively treated. In our patient, a 34-year-old man with poorly controlled type 1 diabetes and autonomic neuropathy manifested by postural hypotension and diarrhea, treatment with diphenhydramine and cimetidine (H1 and H2 histamine antagonists, respectively) markedly improved the hypotension and diarrhea and led to better blood glucose control.
自主神经病变在糖尿病患者中很常见,但很少能得到有效治疗。在我们的患者中,一名34岁男性,1型糖尿病控制不佳且伴有以体位性低血压和腹泻为表现的自主神经病变,使用苯海拉明和西咪替丁(分别为H1和H2组胺拮抗剂)治疗后,低血压和腹泻明显改善,血糖控制也更好。